Top Bio-Pharmaceutical companies and their Pharmacovigilance systems.
| Company | Case Processing | Signaling | REMS | Benefit-Risk Assessment |
| Merck | Oracle Argus | Empirica Signal PV Signal | Custom-built REMS platforms | SAS Analytics |
| Novartis | ArisG | Spotfire (TIBCO) | Veeva Vault Safety | R-based statistical tools |
| CSL Behring | Veeva Vault Safety Suite | Oracle Empirica Signal | Custom REMS solutions | Tableau |
| Pfizer | Oracle Argus | Empirica Signal, Spotfire | Proprietary REMS systems | SAS, Python-based analytics |
| Roche | Oracle Argus | Empirica Signal | Integrated REMS platforms | AI-driven tools |
| AstraZeneca | ArisG | Oracle Empirica Signal | Veeva Vault Safety | Custom analytics platforms |
| Sanofi | Oracle Argus | Empirica Signal | Custom REMS systems | SAS, Tableau |
| Johnson & Johnson | Oracle Argus | Empirica Signal | Custom REMS platforms | SAS Analytics |
| Bristol-Myers Squibb | ArisG | Spotfire (TIBCO) | Proprietary REMS systems | Tableau |
| Eli Lilly | MosaicPV | Empirica Signal | Proprietary REMS systems | Python-based analytics |
| AbbVie | ArisG | Oracle Empirica Signal | Custom REMS solutions | AI-driven tools |
| Gilead Sciences | Oracle Argus | Empirica Signal | Proprietary REMS platforms | Tableau |
| Amgen | Oracle Argus | Empirica Signal | Integrated REMS platforms | SAS, Tableau |
| Novo Nordisk | Oracle Argus | Empirica Signal | Custom REMS systems | Python-based analytics |
| Vertex Pharmaceuticals | ArisG | Oracle Empirica Signal | Custom REMS solutions | SAS, Tableau |
| Genmab | Oracle Argus | Empirica Signal | Custom-built REMS platforms | SAS Analytics |
| Acadia Pharmaceuticals | Veeva Vault Safety | Oracle Empirica Signal | Proprietary REMS systems | Tableau |
| Ascendis Pharma | ArisG | Spotfire (TIBCO) | Custom REMS solutions | AI-driven tools |
| Bluebird Bio | Oracle Argus | Empirica Signal | Custom-built REMS platforms | SAS Analytics |
| Moderna | Veeva Vault Safety | Spotfire (TIBCO) | Proprietary REMS systems | Tableau |
| BioMarin Pharmaceutical | ArisG | Oracle Empirica Signal | Integrated REMS platforms | Python-based analytics |